import smtplib import string host = "localhost" fromclause = "a@b.com" toclause = "c@d.com, e@f.com" toclause = string.splitfields(toclause, ",") msgbody = """ Test! Best Regards """ SMTPServer = smtplib.SMTP(host) SMTPServer.sendmail(fromclause, toclause, msgbody) SMTPServer.quit()